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Chronic cholesterol administration to the brain supports complete and long-lasting cognitive and motor amelioration in Huntington's disease.
Birolini, Giulia; Valenza, Marta; Ottonelli, Ilaria; Talpo, Francesca; Minoli, Lucia; Cappelleri, Andrea; Bombaci, Mauro; Caccia, Claudio; Canevari, Caterina; Trucco, Arianna; Leoni, Valerio; Passoni, Alice; Favagrossa, Monica; Nucera, Maria Rosaria; Colombo, Laura; Paltrinieri, Saverio; Bagnati, Renzo; Duskey, Jason Thomas; Caraffi, Riccardo; Vandelli, Maria Angela; Taroni, Franco; Salmona, Mario; Scanziani, Eugenio; Biella, Gerardo; Ruozi, Barbara; Tosi, Giovanni; Cattaneo, Elena.
Afiliación
  • Birolini G; Department of Biosciences, University of Milan, 20133 Milan, Italy; Istituto Nazionale di Genetica Molecolare "Romeo ed Enrica Invernizzi", 20122 Milan, Italy.
  • Valenza M; Department of Biosciences, University of Milan, 20133 Milan, Italy; Istituto Nazionale di Genetica Molecolare "Romeo ed Enrica Invernizzi", 20122 Milan, Italy. Electronic address: marta.valenza@unimi.it.
  • Ottonelli I; Nanotech Lab, Te.Far.T.I. Center, Department of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
  • Talpo F; Department of Biology and Biotechnologies, University of Pavia, 27100 Pavia, Italy.
  • Minoli L; Pathology Department, Evotec, 37135 Verona, Italy; Mouse & Animal Pathology Lab (MAPLab), Fondazione UniMi, 20139 Milan, Italy.
  • Cappelleri A; Dipartimento di Medicina Veterinaria e Scienze Animali, Università degli Studi di Milano, 26900 Lodi, Italy; Mouse & Animal Pathology Lab (MAPLab), Fondazione UniMi, 20139 Milan, Italy.
  • Bombaci M; Istituto Nazionale di Genetica Molecolare "Romeo ed Enrica Invernizzi", 20122 Milan, Italy.
  • Caccia C; Unit of Medical Genetics and Neurogenetics. Fondazione IRCCS Istituto Neurologico Carlo Besta, 20131 Milan, Italy.
  • Canevari C; Department of Biology and Biotechnologies, University of Pavia, 27100 Pavia, Italy.
  • Trucco A; Department of Biology and Biotechnologies, University of Pavia, 27100 Pavia, Italy.
  • Leoni V; Laboratory of Clinical Chemistry, Hospital Pio XI of Desio, ASST-Brianza and Department of Medicine and Surgery, University of Milano Bicocca, 20900 Monza, Italy.
  • Passoni A; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, 20156 Milan, Italy.
  • Favagrossa M; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, 20156 Milan, Italy.
  • Nucera MR; Department of Biosciences, University of Milan, 20133 Milan, Italy; Istituto Nazionale di Genetica Molecolare "Romeo ed Enrica Invernizzi", 20122 Milan, Italy.
  • Colombo L; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, 20156 Milan, Italy.
  • Paltrinieri S; Dipartimento di Medicina Veterinaria e Scienze Animali, Università degli Studi di Milano, 26900 Lodi, Italy.
  • Bagnati R; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, 20156 Milan, Italy.
  • Duskey JT; Nanotech Lab, Te.Far.T.I. Center, Department of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
  • Caraffi R; Nanotech Lab, Te.Far.T.I. Center, Department of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
  • Vandelli MA; Nanotech Lab, Te.Far.T.I. Center, Department of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
  • Taroni F; Unit of Medical Genetics and Neurogenetics. Fondazione IRCCS Istituto Neurologico Carlo Besta, 20131 Milan, Italy.
  • Salmona M; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, 20156 Milan, Italy.
  • Scanziani E; Dipartimento di Medicina Veterinaria e Scienze Animali, Università degli Studi di Milano, 26900 Lodi, Italy; Mouse & Animal Pathology Lab (MAPLab), Fondazione UniMi, 20139 Milan, Italy.
  • Biella G; Department of Biology and Biotechnologies, University of Pavia, 27100 Pavia, Italy.
  • Ruozi B; Nanotech Lab, Te.Far.T.I. Center, Department of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
  • Tosi G; Nanotech Lab, Te.Far.T.I. Center, Department of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
  • Cattaneo E; Department of Biosciences, University of Milan, 20133 Milan, Italy; Istituto Nazionale di Genetica Molecolare "Romeo ed Enrica Invernizzi", 20122 Milan, Italy. Electronic address: elena.cattaneo@unimi.it.
Pharmacol Res ; 194: 106823, 2023 08.
Article en En | MEDLINE | ID: mdl-37336430
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Enfermedad de Huntington Tipo de estudio: Systematic_reviews Límite: Animals Idioma: En Revista: Pharmacol Res Asunto de la revista: FARMACOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Italia
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Enfermedad de Huntington Tipo de estudio: Systematic_reviews Límite: Animals Idioma: En Revista: Pharmacol Res Asunto de la revista: FARMACOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: Italia