Hypoferremia of inflammation: Innate host defense against infections.
Blood Cells Mol Dis
; 104: 102777, 2024 01.
Article
en En
| MEDLINE
| ID: mdl-37391347
ABSTRACT
Iron is an essential nutrient for microbes, plants and animals. Multicellular organisms have evolved multiple strategies to control invading microbes by restricting microbial access to iron. Hypoferremia of inflammation is a rapidly-acting organismal response that prevents the formation of iron species that would be readily accessible to microbes. This review takes an evolutionary perspective to explore the mechanisms and host defense function of hypoferremia of inflammation and its clinical implications.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Hepcidinas
/
Inflamación
Límite:
Animals
Idioma:
En
Revista:
Blood Cells Mol Dis
Asunto de la revista:
HEMATOLOGIA
Año:
2024
Tipo del documento:
Article