Silencing of long noncoding RNA X-inactive specific transcript alleviates Aß1-42-induced microglia-mediated neurotoxicity by shifting microglial M1/M2 polarization.

Zhao, Kun-Peng; Wang, Xin-Yu; Shao, Mei-Qi; He, Chen-Yang; Yuan, Fu-Qiang

Zhao, Kun-Peng; Wang, Xin-Yu; Shao, Mei-Qi; He, Chen-Yang; Yuan, Fu-Qiang.

Afiliación

Zhao KP; Department of Geriatric Psychiatry, The Second Affiliated Hospital of Xinxiang Medical University, Henan Mental Hospital, Xinxiang, China.
Wang XY; Department of Psychiatry, The Second Affiliated Hospital of Xinxiang Medical University, Henan Mental Hospital, Xinxiang, China.
Shao MQ; Department of Psychiatry, The Second Affiliated Hospital of Xinxiang Medical University, Henan Mental Hospital, Xinxiang, China.
He CY; Department of Geriatric Psychiatry, The Second Affiliated Hospital of Xinxiang Medical University, Henan Mental Hospital, Xinxiang, China.
Yuan FQ; Department of Geriatric Psychiatry, The Second Affiliated Hospital of Xinxiang Medical University, Henan Mental Hospital, Xinxiang, China.

Int J Immunopathol Pharmacol ; 37: 3946320231184988, 2023.

Article en En | MEDLINE | ID: mdl-37400958

Asunto(s)

Enfermedad de Alzheimer; MicroARNs; ARN Largo no Codificante; Ratones; Animales; ARN Largo no Codificante/genética; ARN Largo no Codificante/metabolismo; Microglía; Proteínas Proto-Oncogénicas c-akt/metabolismo; Fosfatidilinositol 3-Quinasas; Enfermedad de Alzheimer/genética; MicroARNs/genética; MicroARNs/metabolismo

Palabras clave

Alzheimer's disease; long noncoding RNA X-inactive specific transcript; microglial polarization; neurotoxicity

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: MicroARNs / Enfermedad de Alzheimer / ARN Largo no Codificante Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Int J Immunopathol Pharmacol Asunto de la revista: ALERGIA E IMUNOLOGIA / FARMACOLOGIA / PATOLOGIA Año: 2023 Tipo del documento: Article País de afiliación: China

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