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CYP5122A1 encodes an essential sterol C4-methyl oxidase in Leishmania donovani and determines the antileishmanial activity of antifungal azoles.
Jin, Yiru; Basu, Somrita; Feng, Mei; Ning, Yu; Munasinghe, Indeewara; Joachim, Arline M; Li, Junan; Madden, Robert; Burks, Hannah; Gao, Philip; Perera, Chamani; Werbovetz, Karl A; Zhang, Kai; Wang, Michael Zhuo.
Afiliación
  • Jin Y; Department of Pharmaceutical Chemistry, School of Pharmacy, The University of Kansas, Lawrence, KS 66047, USA.
  • Basu S; Department of Biological Sciences, Texas Tech University, Lubbock, TX 79409, USA.
  • Feng M; Department of Pharmaceutical Chemistry, School of Pharmacy, The University of Kansas, Lawrence, KS 66047, USA.
  • Ning Y; Department of Biological Sciences, Texas Tech University, Lubbock, TX 79409, USA.
  • Munasinghe I; Synthetic Chemical Biology Core Laboratory, The University of Kansas, Lawrence, KS 66047, USA.
  • Joachim AM; Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA.
  • Li J; College of Pharmacy, The Ohio State University, Columbus, Ohio 43210, USA.
  • Madden R; Department of Biological Sciences, Texas Tech University, Lubbock, TX 79409, USA.
  • Burks H; Department of Biological Sciences, Texas Tech University, Lubbock, TX 79409, USA.
  • Gao P; Protein Production Group, The University of Kansas, Lawrence, KS 66047, USA.
  • Perera C; Synthetic Chemical Biology Core Laboratory, The University of Kansas, Lawrence, KS 66047, USA.
  • Werbovetz KA; Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA.
  • Zhang K; Department of Biological Sciences, Texas Tech University, Lubbock, TX 79409, USA.
  • Wang MZ; Department of Pharmaceutical Chemistry, School of Pharmacy, The University of Kansas, Lawrence, KS 66047, USA.
Res Sq ; 2023 Jul 27.
Article en En | MEDLINE | ID: mdl-37546914

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Res Sq Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Res Sq Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos