Epigenetically upregulating TROP2 and SLFN11 enhances therapeutic efficacy of TROP2 antibody drug conjugate sacitizumab govitecan.

Zhao, Ming; DiPeri, Timothy P; Raso, Maria Gabriela; Zheng, Xiaofeng; Rizvi, Yasmeen Qamar; Evans, Kurt W; Yang, Fei; Akcakanat, Argun; Roberto Estecio, Marco; Tripathy, Debu; Dumbrava, Ecaterina E; Damodaran, Senthil; Meric-Bernstam, Funda

Zhao, Ming; DiPeri, Timothy P; Raso, Maria Gabriela; Zheng, Xiaofeng; Rizvi, Yasmeen Qamar; Evans, Kurt W; Yang, Fei; Akcakanat, Argun; Roberto Estecio, Marco; Tripathy, Debu; Dumbrava, Ecaterina E; Damodaran, Senthil; Meric-Bernstam, Funda.

Afiliación

Zhao M; Department of Investigational Cancer Therapeutics, University of Texas, MD Anderson Cancer Center, Houston, TX, USA.
DiPeri TP; Department of Surgical Oncology, University of Texas, MD Anderson Cancer Center, Houston, TX, USA.
Raso MG; Department of Translational Molecular Pathology, University of Texas, MD Anderson Cancer Center, Houston, TX, USA.
Zheng X; Department of Bioinformatics and Computational Biology, University of Texas, MD Anderson Cancer Center, Houston, TX, USA.
Rizvi YQ; Department of Investigational Cancer Therapeutics, University of Texas, MD Anderson Cancer Center, Houston, TX, USA.
Evans KW; Department of Investigational Cancer Therapeutics, University of Texas, MD Anderson Cancer Center, Houston, TX, USA.
Yang F; Department of Translational Molecular Pathology, University of Texas, MD Anderson Cancer Center, Houston, TX, USA.
Akcakanat A; Department of Investigational Cancer Therapeutics, University of Texas, MD Anderson Cancer Center, Houston, TX, USA.
Roberto Estecio M; Department of Epigenetic and Molecular Carcinogenesis, University of Texas, MD Anderson Cancer Center, Houston, TX, USA.
Tripathy D; Department of Breast Medical Oncology, University of Texas, MD Anderson Cancer Center, Houston, TX, USA.
Dumbrava EE; Department of Investigational Cancer Therapeutics, University of Texas, MD Anderson Cancer Center, Houston, TX, USA.
Damodaran S; Department of Breast Medical Oncology, University of Texas, MD Anderson Cancer Center, Houston, TX, USA.
Meric-Bernstam F; Department of Investigational Cancer Therapeutics, University of Texas, MD Anderson Cancer Center, Houston, TX, USA. fmeric@mdanderson.org.

NPJ Breast Cancer ; 9(1): 66, 2023 Aug 11.

Article en En | MEDLINE | ID: mdl-37567892

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: NPJ Breast Cancer Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

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