The mTORC2/SGK1/NDRG1 Signaling Axis Is Critical for the Mesomesenchymal Transition of Pleural Mesothelial Cells and the Progression of Pleural Fibrosis.

Keshava, Shiva; Owens, Shuzi; Qin, Wenyi; Jeffers, Ann; Kyei, Perpetual; Komatsu, Satoshi; Kleam, Joshua; Ikebe, Mitsuo; Idell, Steven; Tucker, Torry A

Keshava, Shiva; Owens, Shuzi; Qin, Wenyi; Jeffers, Ann; Kyei, Perpetual; Komatsu, Satoshi; Kleam, Joshua; Ikebe, Mitsuo; Idell, Steven; Tucker, Torry A.

Afiliación

Keshava S; Department of Cellular and Molecular Biology, and.
Owens S; Department of Cellular and Molecular Biology, and.
Qin W; Department of Cellular and Molecular Biology, and.
Jeffers A; Texas Lung Injury Institute.
Kyei P; Biotechnology Graduate Program, The University of Texas Health Science Center at Tyler, Tyler, Texas.
Komatsu S; Department of Cellular and Molecular Biology, and.
Kleam J; Department of Cellular and Molecular Biology, and.
Ikebe M; Department of Cellular and Molecular Biology, and.
Idell S; Texas Lung Injury Institute.
Tucker TA; Department of Cellular and Molecular Biology, and.

Am J Respir Cell Mol Biol ; 70(1): 50-62, 2024 Jan.

Article en En | MEDLINE | ID: mdl-37607215

Asunto(s)

Enfermedades Pleurales; Pleuresia; Animales; Ratones; Humanos; Fosfatidilinositol 3-Quinasas/metabolismo; Diana Mecanicista del Complejo 2 de la Rapamicina; Factores de Transcripción; Factor de Crecimiento Transformador beta/metabolismo; Diana Mecanicista del Complejo 1 de la Rapamicina; Fibrosis

Palabras clave

NDRG1; SGK1; TGF-ß; mTORC1/2; mesomesenchymal transition

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Enfermedades Pleurales / Pleuresia Límite: Animals / Humans Idioma: En Revista: Am J Respir Cell Mol Biol Asunto de la revista: BIOLOGIA MOLECULAR Año: 2024 Tipo del documento: Article

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