Clonal dynamics limits detection of selection in tumour xenograft CRISPR/Cas9 screens.

Lee, Tet Woo; Hunter, Francis W; Tsai, Peter; Print, Cristin G; Wilson, William R; Jamieson, Stephen M F

Lee, Tet Woo; Hunter, Francis W; Tsai, Peter; Print, Cristin G; Wilson, William R; Jamieson, Stephen M F.

Afiliación

Lee TW; Auckland Cancer Society Research Centre, University of Auckland, Auckland, New Zealand. tw.lee@auckland.ac.nz.
Hunter FW; Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Auckland, New Zealand. tw.lee@auckland.ac.nz.
Tsai P; Auckland Cancer Society Research Centre, University of Auckland, Auckland, New Zealand.
Print CG; Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Auckland, New Zealand.
Wilson WR; Oncology Therapeutic Area, Janssen Research and Development, Spring House, PA, USA.
Jamieson SMF; Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Auckland, New Zealand.

Cancer Gene Ther ; 30(12): 1610-1623, 2023 12.

Article en En | MEDLINE | ID: mdl-37684549

Asunto(s)

Sistemas CRISPR-Cas; Edición Génica; Humanos; Ratones; Animales; Anciano; Edición Génica/métodos; Xenoinjertos; ARN Guía de Sistemas CRISPR-Cas; Células Clonales

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Sistemas CRISPR-Cas / Edición Génica Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Aged / Animals / Humans Idioma: En Revista: Cancer Gene Ther Asunto de la revista: GENETICA MEDICA / NEOPLASIAS / TERAPEUTICA Año: 2023 Tipo del documento: Article País de afiliación: Nueva Zelanda

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