Replacement of saturated fatty acids with linoleic acid in western diet attenuates atherosclerosis in a mouse model with inducible ablation of hepatic LDL receptor.

Burr, Stephanie D; Chen, Yongbin; Hartley, Christopher P; Zhao, Xianda; Liu, Jun

Burr, Stephanie D; Chen, Yongbin; Hartley, Christopher P; Zhao, Xianda; Liu, Jun.

Afiliación

Burr SD; Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Science, Rochester, MN, 55905, USA.
Chen Y; Division of Endocrinology, Diabetes, Metabolism and Nutrition, Mayo Clinic in Rochester, Guggenheim Building 14-11A, 222 3Rd Avenue SW, Rochester, MN, 55905, USA.
Hartley CP; Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Science, Rochester, MN, 55905, USA.
Zhao X; Department of Laboratory Medicine and Pathology, Mayo Clinic in Rochester, Rochester, MN, 55905, USA.
Liu J; Department of Laboratory Medicine and Pathology, Mayo Clinic in Rochester, Rochester, MN, 55905, USA.

Sci Rep ; 13(1): 16832, 2023 10 06.

Article en En | MEDLINE | ID: mdl-37803087

Asunto(s)

Aterosclerosis; Ácidos Grasos; Ratones; Humanos; Animales; Ácidos Grasos/metabolismo; Ácido Linoleico/metabolismo; Dieta Occidental/efectos adversos; Hígado/metabolismo; Aterosclerosis/patología; Receptores de LDL/genética; Receptores de LDL/metabolismo; Obesidad/metabolismo

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Aterosclerosis / Ácidos Grasos Límite: Animals / Humans Idioma: En Revista: Sci Rep Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos

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