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Efficacy of a Non-Pharmacological Intervention in Seasonal Allergic Rhinitis Symptoms.
Caimmi, Davide; Clark, Evangéline; Fogel, Paul; Heddebaut, Nicolas; Aubier, Michel; Demoly, Pascal.
Afiliación
  • Caimmi D; Department Respiratory Medicine and Allergy, Allergy Unit, Hôpital Arnaud de Villeneuve, University Hospital of Montpellier, Montpellier, France.
  • Clark E; Université de Montpellier, DESP, INSERM, Montpellier, France.
  • Fogel P; Department Respiratory Medicine and Allergy, Allergy Unit, Hôpital Arnaud de Villeneuve, University Hospital of Montpellier, Montpellier, France.
  • Heddebaut N; Université de Montpellier, DESP, INSERM, Montpellier, France.
  • Aubier M; Advestis, Paris, France.
  • Demoly P; Faculty of Medicine, University Paris Cité, Paris, France.
Int Arch Allergy Immunol ; 185(2): 111-115, 2024.
Article en En | MEDLINE | ID: mdl-37926078
BACKGROUND: Patients suffering from allergic rhinitis seek for several therapeutic symptomatic options, including nonconventional treatments, to control their symptoms. OBJECTIVES: Through the present proof-of-concept study, we prospectively investigated the potential role of Puressentiel® nasal protection spray (SNPA) in patients suffering from cypress pollen allergic rhinitis. METHODS: In 15 adults, we performed two nasal provocation tests, with a cypress pollen extract, with a 15-day interval, with and without previous randomized administration of SNPA, and evaluated a nasal symptom score, the nasal inspiratory peak flow, and the concentration of inflammatory cytokines in the nasal lavage after the procedures. RESULTS: Comparing results in patients challenged with and without the SNPA spray before the nasal challenge, we found a 57% mean decrease in symptoms, and a 62% average difference in inspiratory peak flow, after the use of the spray. CONCLUSIONS: Puressentiel® SNPA is effective in reducing nasal symptoms, as assessed by nasal symptoms score and nasal inspiratory peak flow, and could be a valid natural non-pharmacological option in patients suffering from allergic rhinitis.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Rinitis Alérgica Estacional Límite: Adult / Humans Idioma: En Revista: Int Arch Allergy Immunol Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Francia

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Rinitis Alérgica Estacional Límite: Adult / Humans Idioma: En Revista: Int Arch Allergy Immunol Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Francia