Hair Cortisol Concentrations in Opioid-Exposed versus Nonexposed Mother-Infant Dyads.
Am J Perinatol
; 41(8): 1106-1112, 2024 06.
Article
en En
| MEDLINE
| ID: mdl-38160676
ABSTRACT
OBJECTIVE:
To pilot measurement of hair cortisol concentration (HCC) in pregnant women with opioid use disorder and their infants over time and study the potential utility of hair cortisol as a biomarker of chronic stress in this population. STUDYDESIGN:
In this pilot prospective cohort study of mother-infant dyads with and without prenatal opioid exposure, we obtained mother-infant HCCs at delivery and again within 1 to 3 months' postpartum. HCCs were compared between the opioid and control groups and between the two time points.RESULTS:
There were no significant differences between opioid and control group maternal or infant HCCs at either time point. However, within the opioid-exposed group, there was a significant increase in infant HCCs across the two time points.CONCLUSION:
This pilot study describes our experience with the measurement of HCCs in opioid-exposed mother-infant dyads. KEY POINTS · Maternal stress impacts fetal and child health.. · Many stressors in pregnant women with opioid use disorder.. · Hair cortisol may be a useful stress biomarker..
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Estrés Psicológico
/
Hidrocortisona
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Biomarcadores
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Cabello
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Trastornos Relacionados con Opioides
Límite:
Adult
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Female
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Humans
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Infant
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Male
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Newborn
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Pregnancy
Idioma:
En
Revista:
Am J Perinatol
Año:
2024
Tipo del documento:
Article