Understanding Mechanisms of Response to CAR T-cell Therapy through Single-Cell Sequencing: Insights and Challenges.
Blood Cancer Discov
; 5(2): 86-89, 2024 Mar 01.
Article
en En
| MEDLINE
| ID: mdl-38324393
ABSTRACT
SUMMARY:
Single-cell RNA sequencing has emerged as a powerful technique to understand the molecular features of chimeric antigen receptor (CAR) T cells that associate with clinical outcomes. Here we discuss the common themes that have emerged from across single-cell studies of CAR T-cell therapy, and summarize the challenges in interpreting this complex data type.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Investigadores
/
Inmunoterapia Adoptiva
Límite:
Humans
Idioma:
En
Revista:
Blood Cancer Discov
Año:
2024
Tipo del documento:
Article