PI3K/AKT/mTORC1 signalling pathway regulates <i>MMP9</i> gene activation <i>via</i> transcription factor NF-&#954;B in mammary epithelial cells of dairy cows.

Mao, Yongjin; Su, Chen; Yang, Huilin; Ma, Xiaocong; Zhao, Feng; Qu, Bo; Yang, Yang; Hou, Xiaoming; Zhao, Bing; Cui, Yingjun

PI3K/AKT/mTORC1 signalling pathway regulates MMP9 gene activation via transcription factor NF-κB in mammary epithelial cells of dairy cows.

Mao, Yongjin; Su, Chen; Yang, Huilin; Ma, Xiaocong; Zhao, Feng; Qu, Bo; Yang, Yang; Hou, Xiaoming; Zhao, Bing; Cui, Yingjun.

Afiliación

Mao Y; Key Laboratory of Dairy Science of Education Ministry, Northeast Agricultural University, Harbin, PR China.
Su C; Key Laboratory of Dairy Science of Education Ministry, Northeast Agricultural University, Harbin, PR China.
Yang H; Key Laboratory of Dairy Science of Education Ministry, Northeast Agricultural University, Harbin, PR China.
Ma X; Key Laboratory of Dairy Science of Education Ministry, Northeast Agricultural University, Harbin, PR China.
Zhao F; Key Laboratory of Dairy Science of Education Ministry, Northeast Agricultural University, Harbin, PR China.
Qu B; Key Laboratory of Dairy Science of Education Ministry, Northeast Agricultural University, Harbin, PR China.
Yang Y; Key Laboratory of Animal Cellular and Genetics Engineering of Heilongjiang Province, Northeast Agricultural University, Harbin, PR China.
Hou X; Key Laboratory of Animal Cellular and Genetics Engineering of Heilongjiang Province, Northeast Agricultural University, Harbin, PR China.
Zhao B; College of Veterinary Medicine, Northeast Agricultural University, Harbin, PR China.
Cui Y; Key Laboratory of Dairy Science of Education Ministry, Northeast Agricultural University, Harbin, PR China.

Anim Biotechnol ; 35(1): 2314100, 2024 Nov.

Article en En | MEDLINE | ID: mdl-38343377

Asunto(s)

FN-kappa B; Triterpenos Pentacíclicos; Proteínas Proto-Oncogénicas c-akt; Femenino; Bovinos; Animales; FN-kappa B/genética; FN-kappa B/metabolismo; Proteínas Proto-Oncogénicas c-akt/genética; Proteínas Proto-Oncogénicas c-akt/metabolismo; Fosfatidilinositol 3-Quinasas/genética; Metaloproteinasa 9 de la Matriz/genética; Metaloproteinasa 9 de la Matriz/metabolismo; Activación Transcripcional; Diana Mecanicista del Complejo 1 de la Rapamicina/genética; Diana Mecanicista del Complejo 1 de la Rapamicina/metabolismo; Células Epiteliales/metabolismo; Sirolimus/metabolismo; Sirolimus/farmacología

Palabras clave

Dairy cow; NF-κB; mammary epithelial cells; matrix metalloproteinase 9 (MMP9)

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: FN-kappa B / Proteínas Proto-Oncogénicas c-akt / Triterpenos Pentacíclicos Límite: Animals Idioma: En Revista: Anim Biotechnol Asunto de la revista: BIOTECNOLOGIA Año: 2024 Tipo del documento: Article

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