Borna disease in an adult free-ranging Eurasian beaver (Castor fiber albicus).
J Comp Pathol
; 209: 31-35, 2024 Feb.
Article
en En
| MEDLINE
| ID: mdl-38350270
ABSTRACT
Borna disease (BD) associated with a peracute bacterial septicaemia with Escherichia coli was diagnosed in an adult female, naturally infected, free-ranging Eurasian beaver of the subspecies Castor fiber albicus, clinically characterized by weight loss, depression, weakness and gurgled peristaltic sounds. The beaver was euthanized humanely. Necropsy and light microscopy revealed a non-purulent meningoencephalitis with typical mononuclear perivascular cuffs and parenchymal infiltrates. The diagnosis of BD was confirmed by detection of viral antigen and RNA by immunohistochemistry and reverse transcription-polymerase chain reaction (RT-PCR). The PCR product was sequenced and cluster analysis revealed a close relationship between endemic clusters in Saxony-Anhalt. This is the first report of naturally occurring BD in a free-ranging Eurasian beaver.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Enfermedad de Borna
/
Sepsis
/
Meningoencefalitis
Límite:
Animals
Idioma:
En
Revista:
J Comp Pathol
Año:
2024
Tipo del documento:
Article