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Cardioneuroablation for the management of patients with recurrent vasovagal syncope and symptomatic bradyarrhythmias: the CNA-FWRD Registry.
Aksu, Tolga; Tung, Roderick; De Potter, Tom; Markman, Timothy M; Santangeli, Pasquale; du Fay de Lavallaz, Jeanne; Winterfield, Jeffrey R; Baykaner, Tina; Alyesh, Daniel; Joza, Jacqueline E; Gopinathannair, Rakesh; Badertscher, Patrick; Do, Duc H; Hussein, Ayman; Osorio, Jose; Dewland, Thomas; Perino, Alexander; Rodgers, Albert J; DeSimone, Christopher; Alfie, Alberto; Atwater, Brett D; Singh, David; Kumar, Kapil; Salcedo, Jonathan; Bradfield, Jason S; Upadhyay, Gaurav; Sood, Nitesh; Sharma, Parikshit S; Gautam, Sandeep; Kumar, Vineet; Forno, Alexander Romeno Janner Dal; Woods, Christopher E; Rav-Acha, Moshe; Valeriano, Chiara; Kapur, Sunil; Enriquez, Andres; Sundaram, Sri; Glikson, Michael; Gerstenfeld, Edward; Piccini, Jonathan; Tzou, Wendy S; Sauer, William; d'Avila, Andre; Shivkumar, Kalyanam; Huang, Henry D.
Afiliación
  • Aksu T; Department of Cardiology, Yeditepe University Hospital, 34100, Istanbul, Turkey.
  • Tung R; The University of Arizona College of Medicine, Banner-University Medical Center, 755 E McDowell Road, Phoenix, AZ, 85006, USA.
  • De Potter T; Department of Cardiology, OLV Hospital, Aalst, Belgium.
  • Markman TM; Division of Cardiology, University of Pennsylvania, Hospital of the University of Pennsylvania, Philadelphia, USA.
  • Santangeli P; Section of Cardiac Pacing and Electrophysiology, Heart and Vascular Institute, Cleveland Clinic Foundation, Cleveland, OH, USA.
  • du Fay de Lavallaz J; Department of Cardiology, University Hospital Basel, Basel, Switzerland.
  • Winterfield JR; Division of Cardiology, Medical University of South Carolina, Charleston, SC, USA.
  • Baykaner T; Department of Medicine, Division of Cardiovascular Medicine, Stanford University, Stanford, CA, USA.
  • Alyesh D; South Denver Cardiology Associates, 1000 SouthPark Drive, Littleton, CO, 80120, USA.
  • Joza JE; McGill University, Montreal, QC, Canada.
  • Gopinathannair R; Kansas City Heart Rhythm Institute, Overland Park, KS, USA.
  • Badertscher P; Department of Cardiology, University Hospital Basel, Basel, Switzerland.
  • Do DH; University of California Los Angeles (UCLA) Cardiac Arrhythmia Center, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA.
  • Hussein A; Section of Cardiac Pacing and Electrophysiology, Heart and Vascular Institute, Cleveland Clinic Foundation, Cleveland, OH, USA.
  • Osorio J; Arrhythmia Institute at Grandview, Birmingham, AL, USA.
  • Dewland T; Heart Rhythm Clinical Research Solutions, Birmingham, AL, USA.
  • Perino A; Electrophysiology Section, Division of Cardiology, Department of Internal Medicine, University of California, San Francisco, San Francisco, CA, USA.
  • Rodgers AJ; Department of Medicine, Division of Cardiovascular Medicine, Stanford University, Stanford, CA, USA.
  • DeSimone C; Department of Medicine, Division of Cardiovascular Medicine, Stanford University, Stanford, CA, USA.
  • Alfie A; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.
  • Atwater BD; Electrophysiology Section, Cardiology Division, Hospital Nacional Profesor Alejandro Posadas, Av. Illia y Marconi S/N 1684, El Palomar, Moron, Province of Buenos Aires, Argentina.
  • Singh D; Inova Heart and Vascular Institute, Falls Church, VA, USA.
  • Kumar K; The Queens Medical Center, Honolulu, HI, USA.
  • Salcedo J; Harvard Medical School, Boston, MA, USA.
  • Bradfield JS; Palo Alto Medical Foundation-Sutter Health, Palo Alto, CA, USA.
  • Upadhyay G; University of California Los Angeles (UCLA) Cardiac Arrhythmia Center, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA.
  • Sood N; Center for Arrhythmia Care, Section of Cardiology, Pritzker School of Medicine, The University of Chicago Medicine, 5841 S. Maryland Avenue, MC 9024, Chicago, IL, 60637, USA.
  • Sharma PS; Arrhythmia Services, Southcoast Health, Fall River, MA, USA.
  • Gautam S; Department of Cardiology, Rush University Medical Center, Chicago, IL, USA.
  • Kumar V; Department of Cardiac Electrophysiology, University of Missouri-Columbia, Columbia, MO, USA.
  • Forno ARJD; Inova Heart and Vascular Institute, Falls Church, VA, USA.
  • Woods CE; Serviço de Arritmia e Marcapasso - Hospital SOS Cardio - Florianópolis, Florianópolis, SC, Brazil.
  • Rav-Acha M; Department of Cardiology, California Pacific Medical Center, San Francisco, CA, USA.
  • Valeriano C; Jesselson Integrated Heart Center, Shaare Zedek Hospital, 9112102, Jerusalem, Israel.
  • Kapur S; Department of Cardiology, OLV Hospital, Aalst, Belgium.
  • Enriquez A; Cardiac Arrhythmia Service, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Sundaram S; Division of Cardiology, University of Pennsylvania, Hospital of the University of Pennsylvania, Philadelphia, USA.
  • Glikson M; South Denver Cardiology Associates, 1000 SouthPark Drive, Littleton, CO, 80120, USA.
  • Gerstenfeld E; Jesselson Integrated Heart Center, Shaare Zedek Hospital, 9112102, Jerusalem, Israel.
  • Piccini J; Electrophysiology Section, Division of Cardiology, Department of Internal Medicine, University of California, San Francisco, San Francisco, CA, USA.
  • Tzou WS; Duke Clinical Research Institute, Duke University Hospital, Durham, USA.
  • Sauer W; Division of Cardiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
  • d'Avila A; Cardiac Arrhythmia Service, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Shivkumar K; Harvard Medical School, Boston, MA, USA.
  • Huang HD; University of California Los Angeles (UCLA) Cardiac Arrhythmia Center, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA.
J Interv Card Electrophysiol ; 2024 Mar 18.
Article en En | MEDLINE | ID: mdl-38499825
ABSTRACT

BACKGROUND:

Cardioneuroablation has been emerging as a potential treatment alternative in appropriately selected patients with cardioinhibitory vasovagal syncope (VVS) and functional AV block (AVB). However the majority of available evidence has been derived from retrospective cohort studies performed by experienced operators.

METHODS:

The Cardioneuroablation for the Management of Patients with Recurrent Vasovagal Syncope and Symptomatic Bradyarrhythmias (CNA-FWRD) Registry is a multicenter prospective registry with cross-over design evaluating acute and long-term outcomes of VVS and AVB patients treated by conservative therapy and CNA.

RESULTS:

The study is a prospective observational registry with cross-over design for analysis of outcomes between a control group (i.e., behavioral and medical therapy only) and intervention group (Cardioneuroablation). Primary and secondary outcomes will only be assessed after enrollment in the registry. The follow-up period will be 3 years after enrollment.

CONCLUSIONS:

There remains a lack of prospective multicentered data for long-term outcomes comparing conservative therapy to radiofrequency CNA procedures particularly for key outcomes including recurrence of syncope, AV block, durable impact of disruption of the autonomic nervous system, and long-term complications after CNA. The CNA-FWRD registry has the potential to help fill this information gap.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: J Interv Card Electrophysiol Asunto de la revista: CARDIOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Turquía
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: J Interv Card Electrophysiol Asunto de la revista: CARDIOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Turquía