Eosinophilic esophagitis: Current concepts in diagnosis and management.
Saudi J Gastroenterol
; 30(4): 210-227, 2024 Jul 01.
Article
en En
| MEDLINE
| ID: mdl-38752302
ABSTRACT
ABSTRACT Eosinophilic esophagitis is an antigen-mediated chronic inflammatory disorder that has risen in incidence and prevalence over the past 2 decades. The clinical presentation is variable and consists of mainly esophageal symptoms such as dysphagia, heartburn, food impaction, and vomiting. Current management relies on dietary elimination, proton-pump inhibitors, and topical corticosteroids with different response rates and relapses after treatment discontinuation. With a better understanding of the underlying pathophysiology, many molecules emerged recently as targeted treatment including dupilumab (IL4/IL13 blocker), as the first FDA-approved biological treatment, which has changed the management paradigm.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Inhibidores de la Bomba de Protones
/
Esofagitis Eosinofílica
Límite:
Humans
Idioma:
En
Revista:
Saudi J Gastroenterol
/
Saudi j. gastroenterol. (Online)
/
Saudi journal of gastroenterology (Online)
Asunto de la revista:
GASTROENTEROLOGIA
Año:
2024
Tipo del documento:
Article
País de afiliación:
Arabia Saudita