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Sex and Gender-related Disparities in Clinical Characteristics and Outcomes in Heart Transplantation.
Severo Sánchez, Andrea; González Martín, Javier; de Juan Bagudá, Javier; Morán Fernández, Laura; Muñoz Guijosa, Christian; Arribas Ynsaurriaga, Fernando; Delgado, Juan Francisco; García-Cosío Carmena, María Dolores.
Afiliación
  • Severo Sánchez A; Cardiology Department, Hospital Universitario 12 de Octubre, Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), Madrid, Spain.
  • González Martín J; Cardiology Department, Hospital Universitario 12 de Octubre, Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), Madrid, Spain.
  • de Juan Bagudá J; Centro Nacional de Investigaciones Biomédicas en Red de Enfermedades CardioVasculares (CIBERCV), Madrid, Spain.
  • Morán Fernández L; Cardiology Department, Hospital Universitario 12 de Octubre, Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), Madrid, Spain.
  • Muñoz Guijosa C; Centro Nacional de Investigaciones Biomédicas en Red de Enfermedades CardioVasculares (CIBERCV), Madrid, Spain.
  • Arribas Ynsaurriaga F; Department of Medicine, Faculty of Biomedical and Health Sciences, Universidad Europea de Madrid, Madrid, Spain.
  • Delgado JF; Cardiology Department, Hospital Universitario 12 de Octubre, Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), Madrid, Spain.
  • García-Cosío Carmena MD; Centro Nacional de Investigaciones Biomédicas en Red de Enfermedades CardioVasculares (CIBERCV), Madrid, Spain.
Curr Heart Fail Rep ; 21(4): 367-378, 2024 Aug.
Article en En | MEDLINE | ID: mdl-38861129
ABSTRACT
PURPOSE OF REVIEW Limited research has been conducted on sex disparities in heart transplant (HT). The aim of this review is to analyse the available evidence on the influence of sex and gender-related determinants in the entire HT process, as well as to identify areas for further investigation. RECENT

FINDINGS:

Although women make up half of the population affected by heart failure and related mortality, they account for less than a third of HT recipients. Reasons for this inequality include differences in disease course, psychosocial factors, concerns about allosensitisation, and selection or referral bias in female patients. Women are more often listed for HT due to non-ischaemic cardiomyopathy and have a lower burden of cardiovascular risk factors. Although long-term prognosis appears to be similar for both sexes, there are significant disparities in post-HT morbidity and causes of mortality (noting a higher incidence of rejection in women and of malignancy and cardiac allograft vasculopathy in men). Additional research is required to gain a better understanding of the reasons behind gender disparities in eligibility and outcomes following HT. This would enable the fair allocation of resources and enhance patient care.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Trasplante de Corazón / Disparidades en Atención de Salud / Insuficiencia Cardíaca Límite: Female / Humans / Male Idioma: En Revista: Curr Heart Fail Rep Asunto de la revista: CARDIOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: España

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Trasplante de Corazón / Disparidades en Atención de Salud / Insuficiencia Cardíaca Límite: Female / Humans / Male Idioma: En Revista: Curr Heart Fail Rep Asunto de la revista: CARDIOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: España