Excitatory amino acid receptor interactions of a novel alpha-phosphinic acid analogue of alpha-methylaspartic acid.
J Pharm Sci
; 73(11): 1550-3, 1984 Nov.
Article
en En
| MEDLINE
| ID: mdl-6151596
ABSTRACT
An alpha-phosphino analogue of alpha-methylaspartate has been synthesized. The compound may not interact with excitatory amino acid receptors directly, as assessed by direct in vitro radioreceptor binding methods; however, it possesses weak anticonvulsant activity and exhibits an excitant action in vitro that is apparently not mediated by a N-methyl-D-aspartate receptor.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Compuestos Organofosforados
/
Receptores de Superficie Celular
/
Alanina
Límite:
Animals
Idioma:
En
Revista:
J Pharm Sci
Año:
1984
Tipo del documento:
Article