Stimulation of residual insulin secretion by glibenclamide in insulin dependent diabetics.
Acta Endocrinol (Copenh)
; 95(3): 372-5, 1980 Nov.
Article
en En
| MEDLINE
| ID: mdl-6776759
ABSTRACT
Residual insulin secretion, reflected by the presence of C-peptide in serum and urine, has been demonstrated in 5 of 10 insulin-requiring diabetics of less than 10 years' duration tested. The C-peptide response, in the C-peptide secretors, showed a significant increase in both serum and urine after 4 weeks' treatment with 15 mg glibenclamide daily in addition to their usual insulin regime although no beneficial effects in metabolic control were detected. It is suggested that glibenclamide might be a useful adjunct to insulin therapy in insulin-requiring diabetics who still secrete C-peptide.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Gliburida
/
Insulina
Límite:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Acta Endocrinol (Copenh)
Año:
1980
Tipo del documento:
Article