Microecological characteristics of different types of vaginitis and their correlation with HPV infection / 国际生物医学工程杂志

ABSTRACT

Objective:To retrospectively analyze the relationship between different types of vaginal infection, vaginal microecology, and human papillomavirus (HPV) infection.Methods:A retrospective analysis of 6056 patients who underwent vaginal microecology examination was performed, and patients with vaginal infection or HPV detection were screened out. The detection rates of various types of vaginal infection, HPV infection, and infection in different age groups were calculated.Results:A total of 2 737(45.2%) vaginal infection patients were screened, with 7 types of vaginal infection covered. The top three detection rates of vaginal infection were bacterial vaginosis (BV), vulvovaginal candidiasis (VVC), and aerobic vaginal infection (AV). In 6056 patients, 1843 patients underwent HPV detection, among which the top three positive rates of HPV were BV, mixed infection, and VVC. The first three cases of vaginal infection with high-risk HPV infection were BV, mixed infection, and BV intermediate type. The age distribution of different types of vaginal infection combined with HPV infection was different, and the age at which it occurred and the trend of change with age were obvious.Conclusions:BV is closely related to HPV infection. It is suggested that HPV detection should be performed simultaneously in BV patients with vaginal infection, especially those aged 30 to 40 years, which has important clinical significance for HPV screening and prevention.