Recruitment of the auditory cortex in congenitally deaf cats by long-term cochlear electrostimulation.
Science
; 285(5434): 1729-33, 1999 Sep 10.
Article
em En
| MEDLINE
| ID: mdl-10481008
ABSTRACT
In congenitally deaf cats, the central auditory system is deprived of acoustic input because of degeneration of the organ of Corti before the onset of hearing. Primary auditory afferents survive and can be stimulated electrically. By means of an intracochlear implant and an accompanying sound processor, congenitally deaf kittens were exposed to sounds and conditioned to respond to tones. After months of exposure to meaningful stimuli, the cortical activity in chronically implanted cats produced field potentials of higher amplitudes, expanded in area, developed long latency responses indicative of intracortical information processing, and showed more synaptic efficacy than in naïve, unstimulated deaf cats. The activity established by auditory experience resembles activity in hearing animals.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Córtex Auditivo
/
Vias Auditivas
/
Implantes Cocleares
/
Cóclea
/
Surdez
Limite:
Animals
Idioma:
En
Revista:
Science
Ano de publicação:
1999
Tipo de documento:
Article
País de afiliação:
Alemanha