Dementia with Lewy bodies: a pure case.
Brain Cogn
; 44(3): 307-23, 2000 Dec.
Article
em En
| MEDLINE
| ID: mdl-11104528
ABSTRACT
A pure case of autopsy-confirmed dementia with Lewy bodies (DLB) is described. The patient presented with distinctive verbal fluency deficits in the context of mild language impairment, intact recognition memory, and impaired paragraph recall. Neuroimaging (CT and SPECT) showed progressive medial temporal lobe atrophy. Neuropathology revealed Lewy bodies, degeneration in the substantia nigra, nucleus basalis of Meynert (Nakano & Hirano, 1984), and locus ceruleus, but no pathology characteristic of Alzheimer's disease. It is in this sense that the case is "pure" DLB. Early neuropsychological diagnosis of DLB is essential (Salmon et al., 1996) given the potentially fatal hazard of neuroleptics (McKeith et al., 1992) and the difficulties associated with clinical neurological diagnoses (Litvan et al., 1998).
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Encéfalo
/
Doença por Corpos de Lewy
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Demência
Limite:
Aged
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Humans
/
Male
Idioma:
En
Revista:
Brain Cogn
Ano de publicação:
2000
Tipo de documento:
Article
País de afiliação:
Reino Unido