Viewing odors in the mushroom body of the fly.

ABSTRACT

Central processing of olfactory information has been analyzed in the mushroom body of Drosophila by Ca(2+) imaging, extending such analysis of odor coding to the second relay of the olfactory system. Different odors, and different concentrations of a particular odor, yield distinct spatial patterns of activity. Mutations that affect odor receptors and odorant-binding proteins affect these spatial patterns.