IGF -I plasma concentrations in non-treated horses and horses administered with methionyl equine somatotropin.
Res Vet Sci
; 71(3): 167-73, 2001 Dec.
Article
em En
| MEDLINE
| ID: mdl-11798290
ABSTRACT
Insulin-like growth factor-I (IGF -I) is likely to be an indicator of somatotropin (ST) administration in the horse. To investigate the different ways ST administration may be detected, the following aspects of IGF -I concentrations in plasma were studied (i) the daily variation; (ii) variation following a treadmill test; (iii) concentrations at rest and after exercise; and (iv) concentrations in plasma from two young horses and two adults treated with methionyl equine somatotropin (e ST). In the population of horses at rest, IGF -I mean concentration (SEM) was 261 (104) ng ml(-1). In post race samples, IGF -I mean concentration was 187 (100) ng ml(-1). All of these data indicate that exercise does not modify IGF -I concentration in plasma. The magnitude of the increase in IGF -I following administration of e ST differed according to the age of the horses. The critical value of 700 ng ml(-1)was exceeded for 1 day in adult horses and for at least 11 days in young horses. These results show that IGF -I has potential as an indirect marker of ST administration in horses.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fator de Crescimento Insulin-Like I
/
Hormônio do Crescimento
/
Dopagem Esportivo
/
Cavalos
Limite:
Animals
Idioma:
En
Revista:
Res Vet Sci
Ano de publicação:
2001
Tipo de documento:
Article
País de afiliação:
França