Mechanical properties of a reversible, DNA-crosslinked polyacrylamide hydrogel.
J Biomech Eng
; 126(1): 104-10, 2004 Feb.
Article
em En
| MEDLINE
| ID: mdl-15171136
ABSTRACT
Mechanical properties of a polyacrylamide gel with reversible DNA crosslinks are presented. In this system, three DNA strands replace traditional chemical crosslinkers. In contrast to thermoset chemically crosslinked polyacrylamide, the new hydrogel is thermoreversible; crosslink dissociation without the addition of heat is also feasible by introducing a specific removal DNA strand. This hydrogel is characterized by a critical crosslink concentration at which gelation occurs. Below the critical point, a characteristic temperature exists at which a transition in viscosity is observed. Both temperature-dependent viscosity and elastic modulus of the material are functions of crosslink density.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Oligonucleotídeos
/
Resinas Acrílicas
/
Reagentes de Ligações Cruzadas
Tipo de estudo:
Evaluation_studies
Idioma:
En
Revista:
J Biomech Eng
Ano de publicação:
2004
Tipo de documento:
Article
País de afiliação:
Estados Unidos