Apoptotic killing of fibroblasts by matrix-bound advanced glycation endproducts.
Sci Aging Knowledge Environ
; 2005(4): pe3, 2005 Jan 26.
Article
em En
| MEDLINE
| ID: mdl-15673817
ABSTRACT
The extracellular matrix accumulates biologically active advanced glycation endproducts such as carboxymethyl-lysine (CML). Alikhani et al. recently reported that CML-rich collagen, representing an artifically aged matrix protein, induces apoptosis in vivo and in fibroblasts. This observation may have profound implications for the biology of cell-matrix interactions during aging.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Produtos Finais de Glicação Avançada
/
Apoptose
/
Matriz Extracelular
/
Fibroblastos
/
Lisina
Limite:
Animals
Idioma:
En
Revista:
Sci Aging Knowledge Environ
Ano de publicação:
2005
Tipo de documento:
Article
País de afiliação:
Estados Unidos