Thrombolytic therapy for acute stroke in late pregnancy with intra-arterial recombinant tissue plasminogen activator.
Stroke
; 36(6): e53-5, 2005 Jun.
Article
em En
| MEDLINE
| ID: mdl-15914759
ABSTRACT
BACKGROUND AND PURPOSE:
The most common presentation of ischemic stroke related to pregnancy is arterial occlusion, occurring during the third trimester or postpartum. The authors present the first successful administration of intra-arterial cerebral tissue plasminogen activator to treat an embolic cerebral vascular accident in a 37-week parturient resulting in complete recovery of neurological function.METHODS:
The patient presented with left hemiplegia, left-sided neglect, and aphasia. Right internal carotid artery cerebral angiogram showed occlusion of the mid-M1 segment of the middle cerebral artery (MCA). After 15 mg of tissue plasminogen activator was administered via intra-arterial route, there was greatly improved retrograde flow through the posterior communication artery and the MCA territory.RESULTS:
A reduction in size of the MCA occlusion was noted with improvement of antegrade flow through the MCA. Three days after the procedure, the patient was induced successfully and delivered a healthy infant vaginally.CONCLUSIONS:
This report describes the use of intra-arterial tissue plasminogen activator in the setting of stroke in late pregnancy.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Artérias
/
Complicações Cardiovasculares na Gravidez
/
Proteínas Recombinantes
/
Terapia Trombolítica
/
Ativador de Plasminogênio Tecidual
/
Acidente Vascular Cerebral
Limite:
Adult
/
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Stroke
Ano de publicação:
2005
Tipo de documento:
Article
País de afiliação:
Estados Unidos