No significant association of the 5' end of neuregulin 1 and schizophrenia in a large Danish sample.
Schizophr Res
; 83(1): 1-5, 2006 Mar.
Article
em En
| MEDLINE
| ID: mdl-16483744
ABSTRACT
Neuregulin 1 has been implicated as a susceptibility gene in schizophrenia. Several research groups have reported association with the 5' end of the gene although no causative variant has been reported. We have investigated whether there is association with the 5' end of the gene in Danish schizophrenia patients. We found that the at-risk haplotype initially reported in the Icelandic population was not found in significant excess (or = 1.4, p = 0.12). The haplotype structure in the Danish sample was similar to that of other reported in other Caucasian populations and highly different from that of Chinese.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Esquizofrenia
/
Predisposição Genética para Doença
/
Proteínas do Tecido Nervoso
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Limite:
Humans
País/Região como assunto:
Europa
Idioma:
En
Revista:
Schizophr Res
Assunto da revista:
PSIQUIATRIA
Ano de publicação:
2006
Tipo de documento:
Article
País de afiliação:
Dinamarca