Apoptosomes: protease activation platforms to die from.
Trends Biochem Sci
; 31(5): 243-7, 2006 May.
Article
em En
| MEDLINE
| ID: mdl-16595176
ABSTRACT
Apoptosis is orchestrated by members of the caspase family of cysteine proteases that exist as latent pro-enzymes in healthy cells. Caspase-activating platforms, called apoptosomes, initiate caspase activation in metazoans as diverse as nematodes and mammals. Several recent studies have generated new insights into the composition and assembly mechanisms of worm, fly and human apoptosomes.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Apoptose
/
Caspases
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Trends Biochem Sci
Ano de publicação:
2006
Tipo de documento:
Article
País de afiliação:
Irlanda