IL-1 gene polymorphism and periodontal status of HIV Brazilians on highly active antiretroviral therapy.
AIDS
; 20(13): 1779-81, 2006 Aug 22.
Article
em En
| MEDLINE
| ID: mdl-16931944
ABSTRACT
A genotype in the IL-1 gene cluster is associated with an increased risk of periodontitis. We investigated whether polymorphisms in the IL-1A +4845 and IL-1B +3954 loci affect the periodontal status of HIV-infected Brazilians on HAART. HIV-positive and HIV-negative subjects with periodontitis were genotyped for IL-1 by polymerase chain reaction and restriction enzyme digestion. Only 11.4% of patients were genotype positive. No associations between genotype positivity and HIV infection or periodontal status were found in this population.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Periodontite
/
Polimorfismo Genético
/
Infecções por HIV
/
Interleucina-1
/
Terapia Antirretroviral de Alta Atividade
Limite:
Humans
País/Região como assunto:
America do sul
/
Brasil
Idioma:
En
Revista:
AIDS
Assunto da revista:
SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS)
Ano de publicação:
2006
Tipo de documento:
Article
País de afiliação:
Brasil