CSF metabolites in borderline personality disorder compared with normal controls.
Biol Psychiatry
; 28(3): 247-54, 1990 Aug 01.
Article
em En
| MEDLINE
| ID: mdl-1696137
ABSTRACT
Cerebrospinal metabolites were measured in 17 patients with borderline personality disorder and 17 normal controls. There were no significant differences between the two groups in levels of 5-hydroxyindoleacetic acid (5-HIAA), homovanillic acid (HVA), or 3-methoxy-4-hydroxyphenylglycol (MHPG). Within the borderline group, lower levels of CSF 5-HIAA were significantly associated with a history of genuine suicide attempts, but were not associated with violence, self-mutilation, or with the presence of major depression. Thus, CSF 5-HIAA levels are not distinctively low in a diagnostic group characterized by impulsivity and suicidal behavior, but within that group may be associated with genuine suicide attempts.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Suicídio
/
Violência
/
Transtorno da Personalidade Borderline
/
Glicóis
/
Ácido Homovanílico
/
Ácido Hidroxi-Indolacético
/
Metoxi-Hidroxifenilglicol
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
Idioma:
En
Revista:
Biol Psychiatry
Ano de publicação:
1990
Tipo de documento:
Article