Functional mitral regurgitation and chronic heart failure.
Minerva Cardioangiol
; 54(6): 725-33, 2006 Dec.
Article
em En
| MEDLINE
| ID: mdl-17167384
ABSTRACT
Functional mitral regurgitation (MR) frequently develops during the progression of chronic heart failure and predicts poor outcome. Impaired left ventricular (LV) function, LV remodeling associated with papillary muscle apical displacement and annular enlargement result in decreased mitral closing forces and tenting of the mitral valve at closure. Reduced closing forces and tenting both promote MR. Active myocardial ischemia, myocardial asynchronism and excessive loading conditions worsen MR at rest and during exercise. The therapeutic target in functional MR is the left ventricle and not the valve.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Insuficiência Cardíaca
/
Insuficiência da Valva Mitral
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
En
Revista:
Minerva Cardioangiol
Ano de publicação:
2006
Tipo de documento:
Article
País de afiliação:
França