Inflammatory myofibroblastic tumor of the larynx with anaplastic lymphoma kinase (ALK) protein overexpression. A case report.
Tumori
; 92(5): 449-51, 2006.
Article
em En
| MEDLINE
| ID: mdl-17168442
ABSTRACT
Inflammatory myofibroblastic tumor is an uncommon lesion which mainly develops in the lung and is extremely rare in the larynx. It may be easily misinterpreted as a malignant epithelial or mesenchymal spindle cell neoplasm. Histological and clinical knowledge of this lesion is important to exclude misdiagnosis and inappropriate treatment. We report a case of inflammatory myofibroblastic tumor arising on the right vocal cord of a 23-year-old man. The tumor was composed of a mixture of spindle cells and inflammatory elements. Immunohistochemical investigation revealed that the neoplastic cells expressed anaplastic lymphoma kinase (ALK) protein.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Proteínas Tirosina Quinases
/
Neoplasias Laríngeas
/
Neoplasias de Tecido Muscular
Limite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Tumori
Ano de publicação:
2006
Tipo de documento:
Article
País de afiliação:
Itália