IV levetiracetam in the management of non-convulsive status epilepticus.
Neurocrit Care
; 7(1): 36-9, 2007.
Article
em En
| MEDLINE
| ID: mdl-17657655
ABSTRACT
INTRODUCTION:
Status epilepticus (SE) is a medical emergency requiring prompt treatment to try to limit mortality and improve outcome. So far, newer antiepileptic drugs (AED) have not assumed a noticeable role in the treatment of SE. This may be in part due to the lack of IV forms for the newer AEDs. The IV form of Levetiracetam (IV-LEV) has recently become available and has a potential role in the treatment of SE. METHODS ANDRESULTS:
We report two cases of non-convulsive SE that responded favorably to IV-LEV. The first patient is an 83-year-old male with a history of complex partial seizure disorder who presented with impaired consciousness. The second patient is an 82-year-old male with history of old left middle cerebral artery ischemic infarction, who presented with confusion. Both patients were found to have a non-convulsive status epilepticus on electroencephalography (EEG) and treated with IV-LEV. In both cases, electrographic SE stopped with marked clinical improvement. Both patients tolerated the medication well and no significant side effects occurred.CONCLUSION:
IV-LEV may have a potential role in the treatment of non-convulsive status epileptics.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Piracetam
/
Estado Epiléptico
/
Anticonvulsivantes
Tipo de estudo:
Diagnostic_studies
Limite:
Aged80
/
Humans
/
Male
Idioma:
En
Revista:
Neurocrit Care
Assunto da revista:
NEUROLOGIA
/
TERAPIA INTENSIVA
Ano de publicação:
2007
Tipo de documento:
Article
País de afiliação:
Estados Unidos