Evaluation of antiaggressive activity of Eclipta alba in experimental animals.
Pak J Pharm Sci
; 21(2): 195-9, 2008 Apr.
Article
em En
| MEDLINE
| ID: mdl-18390451
ABSTRACT
The occurrence of aggression for prolonged periods of time could have a hazardous impact on the health and social wellbeing of the individual. Aggression can ensue due to exposure to an intimidating situation. Aggression is prominently seen when a disturbance occurs in the fine balance of neurotransmitters such as 5-hydroxytryptamine, gamma- aminobutyric acid, dopamine and their receptor subtypes. The present study investigated the ability of 100 and 200mg/kg of aqueous extract of Eclipta alba to circumvent aggression. Foot shock induced aggression and water competition test were utilized as models for screening of antiaggressive activity. Eclipta alba significantly minimized dominance (p<0.05) which is correlated to the level of aggression particularly with 200mg/kg in the water competition test. A tangible behavioral submission was observed with 100 and 200mg/kg and of Eclipta alba in the foot shock induced test.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Extratos Vegetais
/
Eclipta
/
Agressão
Limite:
Animals
Idioma:
En
Revista:
Pak J Pharm Sci
Assunto da revista:
FARMACIA
/
FARMACOLOGIA
/
QUIMICA
Ano de publicação:
2008
Tipo de documento:
Article