Prediction of sublayer depth in turbid media using spatially offset Raman spectroscopy.
Anal Chem
; 80(21): 8146-52, 2008 Nov 01.
Article
em En
| MEDLINE
| ID: mdl-18785759
ABSTRACT
We demonstrate experimentally the feasibility of monitoring the depth of optically thick layers within turbid media using spatially offset Raman spectroscopy (SORS) in combination with multivariate analysis. The method uses the deep penetration capability of SORS to characterize significantly thicker (by at least a factor of 2) layers than possible with conventional Raman spectroscopy. Typical relative accuracies were between 5 and 10%. The incorporation of depth information into a SORS experiment as an additional dimension allows pure spectra of each individual layer to be resolved using three-dimensional multivariate techniques (parallel factor analysis, PARAFAC) to accuracies comparable with the results of a two-dimensional analysis.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Análise Espectral Raman
/
Nefelometria e Turbidimetria
Tipo de estudo:
Prognostic_studies
/
Risk_factors_studies
Idioma:
En
Revista:
Anal Chem
Ano de publicação:
2008
Tipo de documento:
Article
País de afiliação:
Reino Unido