TSC2 deficiency increases PTEN via HIF1alpha.

Mahimainathan, Lenin; Ghosh-Choudhury, Nandini; Venkatesan, Balachandar; Das, Falguni; Mandal, Chandi C; Dey, Nirmalya; Habib, Samy L; Kasinath, Balakuntalam S; Abboud, Hanna E; Ghosh Choudhury, Goutam

Mahimainathan, Lenin; Ghosh-Choudhury, Nandini; Venkatesan, Balachandar; Das, Falguni; Mandal, Chandi C; Dey, Nirmalya; Habib, Samy L; Kasinath, Balakuntalam S; Abboud, Hanna E; Ghosh Choudhury, Goutam.

Afiliação

Mahimainathan L; Department of Medicine, University of Texas Health Science Center, San Antonio, Texas 78229-3900.
Ghosh-Choudhury N; Veterans Affairs Research, South Texas Veterans Health Care System, San Antonio, Texas 78229; Department of Pathology, University of Texas Health Science Center, San Antonio, Texas 78229-3900.
Venkatesan B; Department of Medicine, University of Texas Health Science Center, San Antonio, Texas 78229-3900.
Das F; Department of Medicine, University of Texas Health Science Center, San Antonio, Texas 78229-3900.
Mandal CC; Department of Pathology, University of Texas Health Science Center, San Antonio, Texas 78229-3900.
Dey N; Department of Medicine, University of Texas Health Science Center, San Antonio, Texas 78229-3900.
Habib SL; Veterans Affairs Research, South Texas Veterans Health Care System, San Antonio, Texas 78229; Geriatric Research, Education, and Clinical Center, South Texas Veterans Health Care System, San Antonio, Texas 78229.
Kasinath BS; Department of Medicine, University of Texas Health Science Center, San Antonio, Texas 78229-3900; Veterans Affairs Research, South Texas Veterans Health Care System, San Antonio, Texas 78229.
Abboud HE; Department of Medicine, University of Texas Health Science Center, San Antonio, Texas 78229-3900; Veterans Affairs Research, South Texas Veterans Health Care System, San Antonio, Texas 78229.
Ghosh Choudhury G; Department of Medicine, University of Texas Health Science Center, San Antonio, Texas 78229-3900; Veterans Affairs Research, South Texas Veterans Health Care System, San Antonio, Texas 78229; Geriatric Research, Education, and Clinical Center, South Texas Veterans Health Care System, San Antonio, Te

J Biol Chem ; 284(41): 27790-27798, 2009 Oct 09.

Article em En | MEDLINE | ID: mdl-19648120

Assuntos

Subunidade alfa do Fator 1 Induzível por Hipóxia/metabolismo; PTEN Fosfo-Hidrolase/metabolismo; Proteínas Supressoras de Tumor/metabolismo; Angiomiolipoma/genética; Angiomiolipoma/metabolismo; Angiomiolipoma/patologia; Animais; Ativação Enzimática; Fibroblastos/citologia; Fibroblastos/fisiologia; Regulação da Expressão Gênica; Humanos; Subunidade alfa do Fator 1 Induzível por Hipóxia/genética; Neoplasias Renais/genética; Neoplasias Renais/metabolismo; Neoplasias Renais/patologia; Camundongos; Camundongos Knockout; PTEN Fosfo-Hidrolase/genética; Regiões Promotoras Genéticas; Proteínas Proto-Oncogênicas c-akt/genética; Proteínas Proto-Oncogênicas c-akt/metabolismo; RNA Interferente Pequeno/genética; RNA Interferente Pequeno/metabolismo; Esclerose Tuberosa/genética; Esclerose Tuberosa/metabolismo; Esclerose Tuberosa/patologia; Proteína 2 do Complexo Esclerose Tuberosa; Proteínas Supressoras de Tumor/deficiência; Proteínas Supressoras de Tumor/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Supressoras de Tumor / PTEN Fosfo-Hidrolase / Subunidade alfa do Fator 1 Induzível por Hipóxia Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2009 Tipo de documento: Article

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