Cutaneous melanoma with metastasis in a cynomolgus monkey (Macaca fascicularis).
J Med Primatol
; 38(6): 444-7, 2009 Dec.
Article
em En
| MEDLINE
| ID: mdl-19793176
ABSTRACT
BACKGROUND:
A 3.3-year-old-male cynomolgus macaque (Macaca fascicularis) showed a focally extensive soft, dark, discoid dermal mass, 0.5 cm in diameter, on the dorsal surface of the right hind foot, over the fourth and fifth metatarsal bones. METHODS AND RESULTS Microscopic examination revealed a cutaneous melanoma with local lymphatic invasion, characterized by neoplastic melanocytes within the subcapsular sinus of popliteal and inguinal lymph nodes. The diagnosis was confirmed by immunohistochemistry and transmission electron microscopy.CONCLUSIONS:
To our knowledge, this is the first documented case of melanoma in a cynomolgus monkey.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pele
/
Neoplasias Cutâneas
/
Macaca fascicularis
/
Melanoma
Limite:
Animals
Idioma:
En
Revista:
J Med Primatol
Ano de publicação:
2009
Tipo de documento:
Article
País de afiliação:
Itália