[Usefulness of pre-surgical biopsy in selecting patients with hepatocellular carcinoma for liver transplant]. / Utilidad de la biopsia preoperatoria en la selección de pacientes con hepatocarcinoma para el trasplante hepático.
Cir Esp
; 87(3): 133-8, 2010 Mar.
Article
em Es
| MEDLINE
| ID: mdl-20074710
ABSTRACT
The selection of patients with hepatocellular carcinoma (HCC) for liver transplantation must be improved. One of the methods proposed to achieve this objective consists of including predictors of tumour aggressiveness to the decision making algorithm. The procedures that would enable this characteristic to be assessed, are 1. Serum biomarkers, 2. Response to transarterial chemoembolisation and 3. Data on the tumour histology. In this review, the available data on the usefulness of each of these procedures are analysed. Special attention is given to the evidence associated with the possible usefulness of a preoperative biopsy. It can be concluded that a preoperative biopsy could be useful to indicate liver transplantation in patients with extended criteria, but not in patients that fulfil the Milan criteria. This scenario could soon change if the initial data on the prognostic value of some molecular markers of tumour progression are confirmed.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cuidados Pré-Operatórios
/
Transplante de Fígado
/
Carcinoma Hepatocelular
/
Seleção de Pacientes
/
Neoplasias Hepáticas
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
Es
Revista:
Cir Esp
Ano de publicação:
2010
Tipo de documento:
Article