Antimicrobial properties of prunin, a citric flavanone glucoside, and its prunin 6â³-O-lauroyl ester.
J Appl Microbiol
; 109(4): 1450-7, 2010 Oct.
Article
em En
| MEDLINE
| ID: mdl-20553344
ABSTRACT
AIMS:
To determine the antimicrobial potential of prunin (P), a flavanone glucoside resulting from the hydrolysis of naringin present in grapefruit, and of its prunin 6â³-O-lauroyl ester (PL), synthesized by enzymatic catalysis. METHODS ANDRESULTS:
P and its lauroyl ester were tested against Gram-negative and Gram-positive bacteria, yeasts and moulds. P showed no inhibitory effect against the micro-organisms assayed, but stimulated growth of Pseudomonas aeruginosa and different Bacilllus sp. However, 150 µg ml(-1) of PL inhibited Escherichia coli, Salmonella enterica serovar Enteritidis, Salmonella enterica serovar Typhimurium, many Bacillus sp., Staphylococcus aureus ATCC29213, Enterococcus avium DSMZ17511, and different Listeria monocytogenes strains. In the last case, L. monocytogenes, sensitive or bacteriocin-resistant cells, lost nearly 4-log reductions after 30 min of contact. A bactericidal mode of action was determined using both scanning and transmission electronic microscopies.CONCLUSIONS:
PL could be used as a food additive, because at low concentration (150 µg ml(-1)) it exhibited antimicrobial activity against important food-borne pathogens. A bactericidal effect was also determined on L. monocytogenes sensitive and bacteriocin-resistant mutant strains. P did not show any antimicrobial property at all. SIGNIFICANCE AND IMPACT OF THE STUDY PL is a potential antimicrobial compound with a high anti-Listeria property.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Florizina
/
Flavanonas
/
Flavonas
/
Glucosídeos
/
Anti-Infecciosos
Idioma:
En
Revista:
J Appl Microbiol
Assunto da revista:
MICROBIOLOGIA
Ano de publicação:
2010
Tipo de documento:
Article
País de afiliação:
Argentina