Exercise dose response in muscle.
Int J Sports Med
; 33(3): 218-23, 2012 Mar.
Article
em En
| MEDLINE
| ID: mdl-22261824
ABSTRACT
Exercise increases peak VO2 partially through muscle adaptations. However, understanding muscle adaptations related to exercise dose is incomplete. This study investigated exercise training dose on capillaries per fiber and capillaries per area; and citrate synthase from vastus lateralis and related both to changes in peak VO2. This randomized trial compared 3 exercise doses low amount-moderate intensity (n=40), low amount-high intensity (n=47), high amount-high intensity (n=41), and a control group (n=35). Both measures of capillary supply increased in all exercise groups (p<0.05). Low amount-high intensity and high amount-high intensity improved citrate synthase (p<0.05) and the low amount-moderate intensity citrate synthase approached significance (p=0.059). Muscle improvements were only related to improvements in peak VO2 in high amount-high intensity (citrate synthase, r=0.304; capillariesfiber, r= - 0.318; p<0.05 and capillaries/mm2 r= - 0.310, p<0.05). These data suggest muscle adaptations occur following both low and high exercise doses, but are only related to improved peak VO2 following high amount-high intensity training.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Consumo de Oxigênio
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Exercício Físico
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Citrato (si)-Sintase
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Músculo Esquelético
Tipo de estudo:
Clinical_trials
Limite:
Adult
/
Female
/
Humans
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Male
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Middle aged
Idioma:
En
Revista:
Int J Sports Med
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Estados Unidos