Sensitive detection of acetaminophen based on Fe3O4 nanoparticles-coated poly(diallyldimethylammonium chloride)-functionalized graphene nanocomposite film.
Talanta
; 88: 181-6, 2012 Jan 15.
Article
em En
| MEDLINE
| ID: mdl-22265485
ABSTRACT
An electrochemical sensor based on Fe(3)O(4) nanoparticles (NPs)-coated poly(diallyldimethylammonium chloride) (PDDA)-functionalized graphene (Fe(3)O(4)-PDDA-G) nanocomposite was fabricated for sensitive detection of acetaminophen. The nanocomposite was characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM) and vibrating sample magnetometer (VSM). The electrochemical behaviors of acetaminophen on Fe(3)O(4)-PDDA-G composite film modified glassy carbon electrode (GCE) were investigated by cyclic voltammetry (CV) and differential pulse voltammetry (DPV). The experimental results indicated that the incorporation of Fe(3)O(4) NPs with PDDA-G greatly enhanced the electrochemical response of acetaminophen. This fabricated sensor displayed excellent analytical performance for acetaminophen detection over a range from 0.1 to 100 µ mol L(-1) with a detection limit of 3.7×10(-8) mol L(-1) (S/N=3). The redox peaks of acetaminophen, dopamine (DA) and ascorbic acid (AA) can be well separated on the Fe(3)O(4)-PDDA-G/GCE. Moreover, the proposed electrochemical sensor also exhibited good reproducibility and stability, and has been used to detect acetaminophen in tablets with satisfactory results.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Polietilenos
/
Óxido Ferroso-Férrico
/
Nanocompostos
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Antipiréticos
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Grafite
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Compostos de Amônio Quaternário
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Analgésicos
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Acetaminofen
Tipo de estudo:
Diagnostic_studies
Idioma:
En
Revista:
Talanta
Ano de publicação:
2012
Tipo de documento:
Article