Structural modeling and biochemical characterization of recombinant KPN_02809, a zinc-dependent metalloprotease from Klebsiella pneumoniae MGH 78578.

Wong, Mun Teng; Choi, Sy Bing; Kuan, Chee Sian; Chua, Siang Ling; Chang, Chiat Han; Normi, Yahaya Mohd; See Too, Wei Cun; Wahab, Habibah A; Few, Ling Ling

Wong, Mun Teng; Choi, Sy Bing; Kuan, Chee Sian; Chua, Siang Ling; Chang, Chiat Han; Normi, Yahaya Mohd; See Too, Wei Cun; Wahab, Habibah A; Few, Ling Ling.

Afiliação

Wong MT; School of Health Sciences, Health Campus, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia.
Choi SB; Pharmaceutical Design and Simulation (PhDS) Laboratory, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Minden 11800, Pulau Pinang, Malaysia.
Kuan CS; School of Health Sciences, Health Campus, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia.
Chua SL; School of Health Sciences, Health Campus, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia.
Chang CH; School of Health Sciences, Health Campus, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia.
Normi YM; Department of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia.
See Too WC; School of Health Sciences, Health Campus, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia.
Wahab HA; Pharmaceutical Design and Simulation (PhDS) Laboratory, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Minden 11800, Pulau Pinang, Malaysia.
Few LL; School of Health Sciences, Health Campus, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia.

Int J Mol Sci ; 13(1): 901-917, 2012.

Article em En | MEDLINE | ID: mdl-22312293

Assuntos

Klebsiella pneumoniae/enzimologia; Metaloproteases/metabolismo; Sequência de Aminoácidos; Sítios de Ligação; Clonagem Molecular; Escherichia coli/metabolismo; Concentração de Íons de Hidrogênio; Metaloproteases/química; Metaloproteases/genética; Simulação de Acoplamento Molecular; Dados de Sequência Molecular; Fenantrolinas/química; Fenantrolinas/metabolismo; Estrutura Terciária de Proteína; Proteínas Recombinantes/biossíntese; Proteínas Recombinantes/química; Proteínas Recombinantes/genética; Alinhamento de Sequência; Temperatura; Zinco/química

Palavras-chave

Klebsiella pneumoniae MGH 78578; homology modeling; hypothetical protein; metalloprotease; metalloprotease inhibitors; molecular docking simulation; ypfJ gene

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Metaloproteases / Klebsiella pneumoniae Tipo de estudo: Prognostic_studies Idioma: En Revista: Int J Mol Sci Ano de publicação: 2012 Tipo de documento: Article País de afiliação: Malásia

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