The key-muscle concept: a long-term low-dose injection strategy for botulinum toxin A treatment in cerebral palsy.
Acta Orthop Belg
; 78(1): 111-6, 2012 Feb.
Article
em En
| MEDLINE
| ID: mdl-22523937
ABSTRACT
Botulinum toxin (BoNT) is a well established treatment in cerebral palsy. A uniform dose strategy is, however, missing. We reviewed 35 children with spastic cerebral palsy treated with BoNT according to a newly-developed Key-Muscle concept. All patients received at least 4 BoNT treatments. Systemic side effects or secondary non-response were not observed. After a mean follow-up of 303 months, none of these patients needed bone surgery whereas 6 underwent soft tissue procedures. The Key-Muscle concept is a safe and effective treatment in spastic cerebral palsy. It respects the need for long-term therapy during motor development. Contractures and lever arm disease can be avoided.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Toxinas Botulínicas Tipo A
/
Fármacos Neuromusculares
Tipo de estudo:
Observational_studies
Limite:
Child
/
Child, preschool
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Acta Orthop Belg
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Alemanha