Healthy women with persistently elevated hCG levels: a case series of fourteen women.
J Reprod Med
; 57(5-6): 249-53, 2012.
Article
em En
| MEDLINE
| ID: mdl-22696821
ABSTRACT
OBJECTIVE:
To review our own data and that in the literature in order to assess likely morbidity and mortality risks and enhance the information that we can provide to patients suffering with this condition. STUDYDESIGN:
This was a retrospective case series using data from the Sheffield Trophoblastic Disease Centre Database combined with data from prior publications.RESULTS:
A diagnosis of elevated human chorionic gonadotropin (hCG) in an otherwise healthy woman carries an 11-19% risk of malignancy and 1-3% risk of mortality. Irrespective of persistently elevated hCG, however, pregnancy appears to be a viable and safe prospect.CONCLUSION:
Persistently elevated hCG in healthy, nonpregnant women is a rare clinical scenario. Due to the rarity of this condition and potential future malignancy risk, we believe that reporting of future cases is crucial, as is a liaison between national and international trophoblastic disease centers, if we are to gain a more thorough understanding of this possibly premalignant condition.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Gonadotropina Coriônica
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Adult
/
Female
/
Humans
/
Middle aged
/
Pregnancy
Idioma:
En
Revista:
J Reprod Med
Ano de publicação:
2012
Tipo de documento:
Article
País de afiliação:
Reino Unido