[Reactive hemophagocytic syndrome: analysis of a series of 7 cases]. / Síndrome hemofagocítico reactivo: análisis de una serie de siete casos.
Med Clin (Barc)
; 94(4): 130-4, 1990 Feb 03.
Article
em Es
| MEDLINE
| ID: mdl-2325464
ABSTRACT
We report a series of seven patients with reactive hemophagocytic syndrome, which was quite characteristic of its etiological spectrum. Infections were the leading cause, among them a case associated with HIV and another one with Salmonella enteritidis (a hitherto unreported association). The clinical findings consisted of fever, hepatomegaly, splenomegaly, lymphadenopathy, rash and pancytopenia. The diagnosis was carried out by bone marrow aspiration-biopsy except in two patients who were diagnosed at autopsy. The difficulty of the differentiation from malignant histiocytosis is discussed one case of hemophagocytic syndrome due to diphenylhydantoin toxicity (the second reported one in the literature) was histologically undistinguishable from it. We think that, in any etiology, hemophagocytic syndrome is a reactive syndrome with variable intensity. The need for extensive microbiological investigation even in cases of histiocytosis of neoplastic appearance is emphasized.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Histiocitose de Células não Langerhans
Limite:
Adult
/
Aged
/
Child
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Female
/
Humans
/
Male
Idioma:
Es
Revista:
Med Clin (Barc)
Ano de publicação:
1990
Tipo de documento:
Article