Cost of prostate image-guided radiation therapy: results of a randomized trial.
Radiother Oncol
; 106(1): 50-8, 2013 Jan.
Article
em En
| MEDLINE
| ID: mdl-23333022
ABSTRACT
PURPOSE:
This cost analysis aimed to quantify the cost of IGRT in relation to IGRT frequency and modality with Cone Beam Computed Tomography (CBCT) or orthogonal electronic portal imaging with fiducial markers (EPI-FM). MATERIAL ANDMETHODS:
Patients undergoing IGRT for localized prostate cancer were randomized into two prostate control frequencies (daily or weekly). Costs were calculated based on the micro-costing results according to hospitals' perspectives (in Euros, 2009) and the time horizon was radiation therapy.RESULTS:
A total of 208 patients were enrolled in seven French cancer centers. A total of 6865 fractions were individually analyzed. The mean total treatment fraction duration was 21.0 min for daily CBCT and 18.3 min for daily EPI-FM. Increasing the control frequency from weekly to daily increased the mean treatment fraction duration by 7.3 min (+53%) for CBCT and 1.7 min (+10%) for EPI-FM (p ≤ 0.01). The mean additional cost per patient of daily controls compared with weekly controls was 679 and 187 for CBCT and EPI-FM, respectively (p<0.0001).CONCLUSIONS:
The incremental costs due to different prostate IGRT strategies are relatively moderate, suggesting that daily IGRT combined with intensity-modulated RT (IMRT) could be administered in cases of high-dose radiation delivery to the prostate.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Próstata
/
Custos de Cuidados de Saúde
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Tomografia Computadorizada de Feixe Cônico
/
Radioterapia Guiada por Imagem
Tipo de estudo:
Clinical_trials
/
Health_economic_evaluation
Limite:
Aged
/
Aged80
/
Humans
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Male
/
Middle aged
Idioma:
En
Revista:
Radiother Oncol
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
França