A vasopressin metabolite increases attentional selectivity.
Behav Neurosci
; 104(2): 277-87, 1990 Apr.
Article
em En
| MEDLINE
| ID: mdl-2346623
ABSTRACT
Two behavioral paradigms were used to assess the effect of a vasopressin metabolite, AVP4-9, on selectivity of attention. The effects observed in a multiple-cue task indicated that AVP4-9 treatment increased the extent to which attention was controlled by the dominant cues in the environment. When these stimuli predicted reward, the peptide treatment facilitated learning, but when these cues were nonpredictive, the treatment hindered learning. In a redundant learning paradigm, administration of the lower dose of AVP4-9 (1 microgram/kg) prevented animals from learning about an added, equally predictive (i.e., redundant) set of cues, suggesting that this treatment caused selective attending to the originally presented stimuli, whose relationship with reward had already been learned. The results of these two studies provide converging evidence that AVP4-9 treatment increases the selectivity of attention, with preferential processing of dominant information. Parallels with the putative attentional effects of increased arousal are discussed.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fragmentos de Peptídeos
/
Atenção
/
Arginina Vasopressina
/
Receptores de Vasopressinas
/
Aprendizagem
Limite:
Animals
Idioma:
En
Revista:
Behav Neurosci
Ano de publicação:
1990
Tipo de documento:
Article