Severe polymyositis due to Toxoplasma gondii in an adult immunocompetent patient: a case report and review of the literature.
Infection
; 41(4): 859-62, 2013 Aug.
Article
em En
| MEDLINE
| ID: mdl-23543435
ABSTRACT
Toxoplasmosis, a worldwide zoonosis caused by a coccidian parasite Toxoplasma gondii, is more often asymptomatic in immunocompetent patients. We report the case of a 38-year-old immunocompetent male with a polymyositis as the presenting manifestation of T. gondii infection. The patient was hospitalized for a 30-day history of fever (T max 39.5°C), muscle pain, and progressive weakness of the muscles. A diagnosis of polymyositis was made, and he was started on corticosteroid treatment, which caused no reduction of symptoms. After finding a positive polymerase chain reaction (PCR) assay for T. gondii, together with additional clinical findings, a diagnosis of acute toxoplasmosis was made. Specific treatment with pyrimethamine and sulfadiazine was started, with a progressive reduction of symptoms and normalization of laboratory tests.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Toxoplasma
/
Toxoplasmose
/
Polimiosite
Limite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Infection
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Itália