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Severe polymyositis due to Toxoplasma gondii in an adult immunocompetent patient: a case report and review of the literature.
Cuomo, G; D'Abrosca, V; Rizzo, V; Nardiello, S; La Montagna, G; Gaeta, G B; Valentini, G.
Afiliação
  • Cuomo G; Infectious Disease Section, Department of Clinical and Experimental Medicine, Second University of Naples, Naples, Italy.
Infection ; 41(4): 859-62, 2013 Aug.
Article em En | MEDLINE | ID: mdl-23543435
ABSTRACT
Toxoplasmosis, a worldwide zoonosis caused by a coccidian parasite Toxoplasma gondii, is more often asymptomatic in immunocompetent patients. We report the case of a 38-year-old immunocompetent male with a polymyositis as the presenting manifestation of T. gondii infection. The patient was hospitalized for a 30-day history of fever (T max 39.5°C), muscle pain, and progressive weakness of the muscles. A diagnosis of polymyositis was made, and he was started on corticosteroid treatment, which caused no reduction of symptoms. After finding a positive polymerase chain reaction (PCR) assay for T. gondii, together with additional clinical findings, a diagnosis of acute toxoplasmosis was made. Specific treatment with pyrimethamine and sulfadiazine was started, with a progressive reduction of symptoms and normalization of laboratory tests.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Toxoplasma / Toxoplasmose / Polimiosite Limite: Adult / Humans / Male Idioma: En Revista: Infection Ano de publicação: 2013 Tipo de documento: Article País de afiliação: Itália

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Toxoplasma / Toxoplasmose / Polimiosite Limite: Adult / Humans / Male Idioma: En Revista: Infection Ano de publicação: 2013 Tipo de documento: Article País de afiliação: Itália