Management and outcome of pallidal deep brain stimulation in severe Huntington's disease.
Fortschr Neurol Psychiatr
; 81(4): 202-5, 2013 Apr.
Article
em En
| MEDLINE
| ID: mdl-23589113
ABSTRACT
Neurodegenerative movement disorders, such as Huntington's disease (HD), have become a promising field for Deep Brain Stimulation (DBS). This study aims to contribute to the establishment of a well-grounded database including both expected and unexpected effects of pallidal DBS in HD, and to discuss the ethical and legal restrictions of DBS in cognitively limited patients. Evaluation of the outcome data indicates that pallidal DBS exerted an independent effect on motor symptoms but probably also on the patient's cognitive and affective state. The cognitive decline, however, that characterizes the late stage of neurodegenerative disorders implicates ethical and legal problems given the patients' inability to give informed consent to DBS.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doença de Huntington
/
Estimulação Encefálica Profunda
/
Globo Pálido
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
Limite:
Adult
/
Female
/
Humans
Idioma:
En
Revista:
Fortschr Neurol Psychiatr
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Alemanha