Your browser doesn't support javascript.
loading
Response of testosterone to prolonged aerobic exercise during different phases of the menstrual cycle.
O'Leary, C B; Lehman, C; Koltun, K; Smith-Ryan, A; Hackney, A C.
Afiliação
  • O'Leary CB; Applied Physiology Laboratory, Department of Exercise and Sport Science, University of North Carolina, CB # 8700 Fetzer Hall, Chapel Hill, NC 27599, USA. coleary@live.unc.edu
Eur J Appl Physiol ; 113(9): 2419-24, 2013 Sep.
Article em En | MEDLINE | ID: mdl-23812088
ABSTRACT

PURPOSE:

To examine the androgen response to exercise in women under conditions of high (H) and low (L) estrogen (E2) levels.

METHODS:

Ten exercise trained eumenorrheic women (mean ± SD 20.0 ± 2.2 years, 58.7 ± 8.3 kg, 22.3 ± 4.9 % body fat, VO2max = 50.7 ± 9.0 mL/kg/min) completed a 60 min treadmill run at ~70 % of VO2max during both the mid-follicular (L-E2, 69.7 ± 7.3 % VO2max) and mid-luteal (H-E2, 67.6 ± 7.9 % VO2max) phases of their menstrual cycle. Blood samples were taken pre-exercise (PRE), immediately post (POST), and 30 min into recovery (30R) from exercise and analyzed for total testosterone using ELISA assays. Results were analyzed using repeated measures ANOVA.

RESULTS:

Testosterone responses were (mean ± SD L-E2, pre = 1.41 ± 0.21, post = 1.86 ± 0.21, 30R = 1.75 ± 0.32 nmol/L; H-E2, pre = 1.27 ± 0.23, post = 2.43 ± 0.56, 30R = 1.69 ± 0.34 nmol/L). Statistical analysis indicated no significant interaction existed between high and low estrogen conditions across the blood sampling times (p = 0.138). However, a main effect occurred for exercise (p < 0.004) with the post-testosterone concentration being greater than pre, although pre vs. 30R was not different (p > 0.05). All testosterone hormonal concentrations immediately post-exercise greatly exceeded the level of hemoconcentration observed during the L-E2 and H-E2 exercise sessions.

CONCLUSIONS:

Prolonged aerobic exercise induces short-term elevations in testosterone in trained eumenorrheic women, which appears unrelated to estrogen levels and menstrual cycle phase. These increases may occur due to either increased androgen production and/or decreased degradation rates of the hormone, and are not solely the result of plasma fluid shifts from the exercise.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Testosterona / Exercício Físico / Ciclo Menstrual Limite: Adult / Female / Humans Idioma: En Revista: Eur J Appl Physiol Assunto da revista: FISIOLOGIA Ano de publicação: 2013 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Testosterona / Exercício Físico / Ciclo Menstrual Limite: Adult / Female / Humans Idioma: En Revista: Eur J Appl Physiol Assunto da revista: FISIOLOGIA Ano de publicação: 2013 Tipo de documento: Article País de afiliação: Estados Unidos